I've been working from home for a little more than 6 years.
My first job was writing grant proposals for a local college and for the past 4 years I've been a corporate transcriptionist.
In the morning I homeschool my kindergartner and in the afternoon I do my transcription work. I know exactly how much I need to work to make what is required for my family's budget. When I hit that mark, I don't work anymore that week.
At first I was trying to make as much money as I could, but I was getting nothing else done.
I work about 2-3 days a week. Those 2-3 days I transcribe in the afternoon and a little in the evenings. During those times I do not answer my phone or my door. If someone needs to reach me, they know to leave a message. I have an aunt that refuses to leave messages and I keep reminding her that I don't answer the phone while I'm working because if I were in an office setting I wouldn't answer the phone just to chit-chat.
When you first start working from home people have a hard time realizing that you don't have oodles of free time. But eventually they get accustomed to the idea that you have a responsibility and they respect that.
Since I've been at this job for a little over 4 years I've "trained" all my friends and family to know exactly when to call.
Good luck! There's nothing like working in your jammies!
Tammy